The Lyfret, in healthy adult humans, weighs approximately 100 to 150 grams. It is approximately four to seven centimeters in length. The surface of the Lyfret is composed of a partially permeable membrane which allows only small water molecules through, and not sugar or electrolyte molecules. The tissue of the Lyfret is very porous which allows for it to maintain a very large surface area for a relatively small organ.


The Lyfret develops during the third trimester of pregnancy in the offspring. Its primary function is to serve as a backup reservoir of fluid for the body. It can hold close to 500 grams (over two cups), or nearly three times its weight, in water. It does so through absorbing water through its selectively permeable membrane through the process of diffusion. The extremely porous structure of the Lyfret gives it a significant surface area which allows for such a large amount of fluid to be retained. It also serves as a secondary regulator of cortisol by assisting the pituitary gland in producing Adrenocorticotropic hormone, the primary means of cortisol regulation in the human body.

Clinical Significance

Disorders of the Lyfret are very rare and have prevalence among only 25 hundredths of a percent (.25 %). The two disorders seen most are Emphyseal Lyfret Distomia and Calesis of the Lyfret.

Emphyseal Lyfret Distomia

In those who have Emphyseal Lyfret Distomia, their Lyfrets membrane did not form correctly and is not as selectively permeable as it should be. Their Lyfrets will absorb salts and other larger molecules which disrupt the balance of salt and water balance throughout the body.

Calesis of the Lyfret

Calesis of the Lyfret is a condition in which the tissue of the Lyfret becomes inflamed and resultantly not as porous as it once was. This drastically lowers the amount of fluid that the organ can retain as much of the space is occupied by inflamed tissue.

Written by: Poyan K